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DC Field | Value | Language |
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dc.contributor.author | Hernández, Sergi | - |
dc.contributor.author | Moraga Llop, Fernando A. | - |
dc.contributor.author | Díaz, A. | - |
dc.contributor.author | de Sevilla, Mariona F. | - |
dc.contributor.author | Ciruela, Pilar | - |
dc.contributor.author | Muñoz Almagro, Carmen | - |
dc.contributor.author | Codina Grau, Maria Gemma | - |
dc.contributor.author | Campins Martí, Magda | - |
dc.contributor.author | García García, Juan José | - |
dc.contributor.author | Esteva, Cristina | - |
dc.contributor.author | Izquierdo, Conchita | - |
dc.contributor.author | González Peris, Sebastià | - |
dc.contributor.author | Martínez Osorio, Johanna | - |
dc.contributor.author | Uriona, Sonia | - |
dc.contributor.author | Salleras i Sanmartí, Lluís | - |
dc.contributor.author | Domínguez, Angela | - |
dc.date.accessioned | 2023-03-27T17:59:20Z | - |
dc.date.available | 2023-03-27T17:59:20Z | - |
dc.date.issued | 2020-06 | - |
dc.identifier.issn | 1080-6040 | - |
dc.identifier.uri | http://hdl.handle.net/2445/196032 | - |
dc.description.abstract | Vaccination with the 13-valent conjugated pneumococcal disease (PCV13) has reduced invasive pneumococcal disease (IPD), but there have been reports of vaccine failures. We performed a prospective study in children aged 2-59 months who received diagnoses of IPD during January 2012-June 2016 in 3 pediatric hospitals in Catalonia, Spain, a region with a PCV13 vaccination coverage of 63%. We analyzed patients who had been age-appropriately vaccinated but who developed IPD caused by PCV13 serotypes. We detected 24 vaccine failure cases. The serotypes involved were 3 (16 cases); 19A (5 cases); and 1, 6B, and 14 (1 case each). Cases were associated with children without underlying conditions, with complicated pneumonia (OR 6.65, 95% CI 1.91-23.21), and with diagnosis by PCR (OR 5.18, 95% CI 1.84-14.59). Vaccination coverage should be increased to reduce the circulation of vaccine serotypes. Continuous surveillance of cases of IPD using both culture and PCR to characterize vaccine failures is necessary. | - |
dc.format.extent | 9 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | Centers for Disease Control and Prevention | - |
dc.relation.isformatof | Reproducció del document publicat a: https://doi.org/10.3201/eid2606.190951 | - |
dc.relation.ispartof | Emerging Infectious Diseases, 2020, vol. 26, num. 6, p. 1147-1155 | - |
dc.relation.uri | https://doi.org/10.3201/eid2606.190951 | - |
dc.rights | Domini públic / Public domain | - |
dc.rights.uri | https://creativecommons.org/publicdomain/mark/1.0/ | - |
dc.source | Articles publicats en revistes (Cirurgia i Especialitats Medicoquirúrgiques) | - |
dc.subject.classification | Reacció en cadena de la polimerasa | - |
dc.subject.classification | Espanya | - |
dc.subject.classification | Pneumococs | - |
dc.subject.classification | Vacunes antibacterianes | - |
dc.subject.classification | Pneumònia | - |
dc.subject.classification | Infeccions respiratòries | - |
dc.subject.classification | Infeccions per estreptococs | - |
dc.subject.classification | Vacunació dels infants | - |
dc.subject.other | Polymerase chain reaction | - |
dc.subject.other | Spain | - |
dc.subject.other | Streptococcus pneumonia | - |
dc.subject.other | Bacterial vaccines | - |
dc.subject.other | Pneumonia | - |
dc.subject.other | Respiratory infections | - |
dc.subject.other | Streptococcal infections | - |
dc.subject.other | Vaccination of children | - |
dc.title | Failures of 13-Valent Conjugated Pneumococcal Vaccine in Age-Appropriately Vaccinated Children 2-59 Months of Age, Spain | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/publishedVersion | - |
dc.identifier.idgrec | 702112 | - |
dc.date.updated | 2023-03-27T17:59:20Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
Appears in Collections: | Articles publicats en revistes (Cirurgia i Especialitats Medicoquirúrgiques) Articles publicats en revistes (Medicina) |
Files in This Item:
File | Description | Size | Format | |
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702112.pdf | 459.72 kB | Adobe PDF | View/Open |
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