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https://dipositint.ub.edu/dspace/handle/2445/201872| Title: | The reversibility of cellular mechano-activation |
| Author: | Beedle, Amy EM. Roca Cusachs, Pere |
| Keywords: | Transducció de senyal cel·lular Fisiologia cel·lular Cellular signal transduction Cell physiology |
| Issue Date: | 1-Oct-2023 |
| Publisher: | Elsevier BV |
| Citation: | Beedle AE;Roca-Cusachs P. The reversibility of cellular mechano-activation. Current Opinion In Cell Biology, 2023, 84, 102229-NA |
| Abstract: | The cellular microenvironment is highly heterogeneous and dynamic. Therefore, cells must be equipped with molecular tools to adapt and respond to constantly fluctuating inputs. One such input is mechanical force, which activates signalling and regulates cell behaviour in the process of mechanotransduction. Whereas the mechanisms activating mechanotransduction are well studied, the reversibility of this process, whereby cells disassemble and reverse force-activated signalling pathways upon cessation of mechanical stimulation is far less understood. In this review we will outline some of the key experimental techniques to investigate the reversibility of mechanical signalling, and key discoveries arising from them.Copyright © 2023 The Authors. Published by Elsevier Ltd.. All rights reserved. |
| Note: | https://doi.org/10.1016/j.ceb.2023.102229 |
| It is part of: | Current Opinion In Cell Biology, 2023, vol. 84 |
| URI: | https://hdl.handle.net/2445/201872 |
| Related resource: | https://doi.org/10.1016/j.ceb.2023.102229 |
| ISSN: | 1879-0410 |
| Appears in Collections: | Articles publicats en revistes (Institut de Bioenginyeria de Catalunya (IBEC)) |
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| File | Description | Size | Format | |
|---|---|---|---|---|
| 2023_CurOpiCelBio_TheReversibility_BeedleA.pdf | 882.71 kB | Adobe PDF | View/Open |
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