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https://dipositint.ub.edu/dspace/handle/2445/48193
Title: | Nanocharacterization of Soft Biological Samples in Shear Mode with Quartz Tuning Fork Probes |
Author: | Otero Díaz, Jorge Gonzalez Claramonte, Laura Puig i Vidal, Manuel |
Keywords: | Microscòpia de força atòmica Citologia Nanotecnologia Biomolècules Bacteris Bioenginyeria Atomic force microscopy Cytology Nanotechnology Biomolecules Bacteria Bioengineering |
Issue Date: | 24-Mar-2012 |
Publisher: | MDPI Publishing |
Abstract: | Quartz tuning forks are extremely good resonators and their use is growing in scanning probe microscopy. Nevertheless, only a few studies on soft biological samples have been reported using these probes. In this work, we present the methodology to develop and use these nanosensors to properly work with biological samples. The working principles, fabrication and experimental setup are presented. The results in the nanocharacterization of different samples in different ambients are presented by using different working modes: amplitude modulation with and without the use of a Phase-Locked Loop (PLL) and frequency modulation. Pseudomonas aeruginosa bacteria are imaged in nitrogen using amplitude modulation. Microcontact printed antibodies are imaged in buffer using amplitude modulation with a PLL. Finally, metastatic cells are imaged in air using frequency modulation. |
Note: | Reproducció del document publicat a: http://dx.doi.org/10.3390/s120404803 |
It is part of: | Sensors, 2012, vol. 12, p. 4803-4819 |
URI: | http://hdl.handle.net/2445/48193 |
Related resource: | http://dx.doi.org/10.3390/s120404803 |
ISSN: | 1424-8220 |
Appears in Collections: | Articles publicats en revistes (Enginyeria Electrònica i Biomèdica) |
Files in This Item:
File | Description | Size | Format | |
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612068.pdf | 1.83 MB | Adobe PDF | View/Open |
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