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https://dipositint.ub.edu/dspace/handle/2445/54707| Title: | Orthogonal protecting groups in the synthesis of tryptophanyl-hexahydropyrroloindoles |
| Author: | Ruiz Sanchis, Pau Savina, Svetlana A. Acosta, Gerardo A. Albericio Palomera, Fernando Álvarez Domingo, Mercedes |
| Keywords: | Productes naturals marins Química heterocíclica Aminoàcids Síntesi de pèptids Marine natural products Heterocyclic chemistry Amino acids Peptide synthesis |
| Issue Date: | 22-Nov-2011 |
| Publisher: | Wiley-VCH |
| Abstract: | The synthesis of various polycyclic systems containing a C3a-Ni bond between a hexahydropyrrolo[2,3-b]indole and an indole tryptophan is described here. A series of experiments were performed to determine the best combination of five orthogonal protecting groups and the best reaction conditions for formation of said bond, which is a common feature among many recently discovered marine natural products. |
| Note: | Versió preprint del document publicat a: http://dx.doi.org/10.1002/ejoc.201101057 |
| It is part of: | European Journal of Organic Chemistry, 2012, vol. 2012, num. 1, p. 67-73 |
| URI: | https://hdl.handle.net/2445/54707 |
| Related resource: | http://dx.doi.org/10.1002/ejoc.201101057 |
| ISSN: | 1434-193X |
| Appears in Collections: | Articles publicats en revistes (Farmacologia, Toxicologia i Química Terapèutica) |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| 598515.pdf | 2.18 MB | Adobe PDF | View/Open |
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