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DC Field | Value | Language |
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dc.contributor.author | Martín Venegas, Raquel | - |
dc.contributor.author | Brufau Bonet, M. Teresa (Maria Teresa) | - |
dc.contributor.author | Ferrer i Roig, Ruth | - |
dc.date.accessioned | 2015-03-12T18:35:44Z | - |
dc.date.available | 2015-03-12T18:35:44Z | - |
dc.date.issued | 2014 | - |
dc.identifier.uri | http://hdl.handle.net/2445/63973 | - |
dc.description | Podeu consultar el llibre complet a: http://hdl.handle.net/2445/63704 | ca |
dc.description.abstract | Intestinal infection with Salmonella enterica serotype Enteritidis, a food-borne infection spread to humans especially through contaminated eggs and egg-products as well as undercooked contaminated fresh meat, is the most common cause of intestinal inflammation in the European Union. Enteritis caused by Salmonella Enteritidis is characterized by fever, diarrhoea and abdominal pain. The disruption of the intestinal epithelial barrier function contributes to diarrhoea and is responsible for the perpetuation of the inflammatory process. In this sense, oxidative stress and the proinflammatory cytokines TNF-α, IFN-γ and IL-1β are described to induce the disorganization of the tight junctions (TJ), the most apical epithelial intercellular junctions and responsible for the paracellular permeability. The interest of this chapter relies not only in the investigation dealing with the mechanisms of TJ regulation but also in the contribution to the development of new tools for the prevention of epithelial barrier disruption in enteritis caused by Salmonella Enteritidis. | ca |
dc.format.extent | 12 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | ca |
dc.publisher | Research Signpost | ca |
dc.relation.isformatof | Reproducció del capítol del llibre publicat a: http://www.trnres.com/ebookcontents.php?id=234 | - |
dc.relation.ispartof | Recent Advances in Pharmaceutical Sciences IV, 2014, Research Signpost : Editors: Diego Muñoz Torrero, Manuel Vázquez-Carrera & Joan Estelrich i Latràs. ISBN: 978-81-308-0554-2. Chapter 5, p. 73-84. | - |
dc.relation.uri | http://hdl.handle.net/2445/63704 | - |
dc.rights | (c) Research Signpost, 2014 | - |
dc.source | Llibres / Capítols de llibre (Bioquímica i Fisiologia) | - |
dc.subject.classification | Salmonel·la | cat |
dc.subject.classification | Enteritis | cat |
dc.subject.classification | Malalties inflamatòries intestinals | cat |
dc.subject.classification | Fisiologia patològica | - |
dc.subject.other | Salmonella | eng |
dc.subject.other | Enteritis | eng |
dc.subject.other | Inflammatory bowel diseases | - |
dc.subject.other | Pathological physiology | - |
dc.title | Loss of intestinal epithelial barrier function in Salmonella Enteritidis infection | ca |
dc.type | info:eu-repo/semantics/bookPart | ca |
dc.type | info:eu-repo/semantics/publishedVersion | - |
dc.identifier.idgrec | 290545 | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | ca |
Appears in Collections: | Llibres / Capítols de llibre (Bioquímica i Fisiologia) |
Files in This Item:
File | Description | Size | Format | |
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T_1422618464Munoz-Torrero 5.pdf | 315.42 kB | Adobe PDF | View/Open |
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